Product Name :
SENP6 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
SENP6 antibody KIAA0797 antibody SSP1 antibody SUSP1 antibody FKSG6 antibody Sentrin-specific protease 6 antibody SUMO-1-specific protease 1 antibody Sentrin/SUMO-specific protease SENP6 antibody
Function :
Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al. 2000). SENPs also display isopeptidase activity for
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SENP6. AA range:1042-1091
Species reactivity:
Human
Verify application:
IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.1190861-74-5 manufacturer Aliquot store at -20℃ or -80℃.2791273-76-0 Chemscene Avoid repeated freeze / thaw cycles.PMID:33712886
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Positive control :
Brain,Epithelium,Testis,Tongue,Whole embryo,