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Phospho-Smad2 (S250) Recombinant Rabbit Monoclonal Antibody [SD207-1]

By Chemexpress

Product Name :
Phospho-Smad2 (S250) Recombinant Rabbit Monoclonal Antibody [SD207-1]

Predicted band size :
52 kDa

Observed band size :
55 kDa

Synonyms:
Drosophila, homolog of, MADR2 antibody hMAD-2 antibody HsMAD2 antibody JV18 antibody JV18-1 antibody JV181 antibody MAD antibody MAD homolog 2 antibody MAD Related Protein 2 antibody Mad-related protein 2 antibody 展开

Function :
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and Activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to Activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Synthetic phospho-peptide corresponding to residues surrounding Ser250 of Human Smad2 aa 221-270 / 467.

Species reactivity:
Human, Mouse, Rat

Verify application:
WB, FC, IP

Coupling :
unconjugated

Clone number:
SD207-1

RRID:
AB_3070105

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.Price of 1415559-47-5

Subtype:
IgG

Purification method :
Protein A affinity purified.(4-(Ethylsulfonyl)phenyl)methanamine site

ELTSA :

Molecular weight :
Predicted band size: 52 kDa

Positive control :
HeLa cell lysate, HeLa treated with 200nM PMA for 30 minutes cell lysate, NIH/3T3 cell lysate, NIH/3T3 treated with 200nM PMA for 30 minutes cell lysate, C6 cell lysate, C6 treated with 200nM PMA for 30 minutes cell lysate, HeLa.PMID:33559014

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