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PIST Recombinant Rabbit Monoclonal Antibody [JG79-35]

By Chemexpress

Product Name :
PIST Recombinant Rabbit Monoclonal Antibody [JG79-35]

Predicted band size :
51 kDa

Observed band size :
55 kDa

Synonyms:
CAL antibody CFTR associated ligand antibody CFTR-associated ligand antibody dJ94G16.2 antibody dJ94G16.2 PIST antibody FIG antibody Fused in glioblastoma antibody Golgi associated PDZ and coiled coil motif containing antibody Golgi associated PDZ and coiled coil motif containing protein antibody Golgi-associated PDZ and coiled-coil motif-containing protein antibody 展开

Function :
PIST (PDZ protein interacting specifically with TC10), also known as GOPC (golgi associated PDZ and coiled-coil motif containing), CAL or FIG, is a 462 amino acid protein that localizes to the cytoplasm, as well as to the membrane of the golgi apparatus and to the cell junction. Expressed ubiquitously and containing one PDZ (DHR) domain, PIST functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, PIST is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy.tert-Butyl hept-6-ynoate web Chromosomal aberrations in the gene encoding PIST are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Three isoforms of PIST exist due to alternative splicing events.

Antibody Type:
Recombinant Rabbit monoclonal Antibody

Immunogen :
Recombinant protein within Human PIST aa 1-140 / 462.846548-44-5 custom synthesis

Species reactivity:
Human, Mouse

Verify application:
WB, IF-Cell, IF-Tissue, IP, IHC-P, FC

Coupling :
unconjugated

Clone number:
JG79-35

RRID:
AB_3070856

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.PMID:33663354 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
51 kDa

Positive control :
SiHa cell lysates, HepG2, MCF-7, SKOV-3, human liver carcinoma tissue, human colon tissue, human kidney tissue, mouse brain tissue.

By Chemexpress

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