Product Name :
TNFRSF18 Mouse Monoclonal Antibody [4H2D6]
Predicted band size :
Observed band size :
Synonyms:
Activation inducible TNFR family receptor antibody Activation-inducible TNFR family receptor antibody AITR antibody CD357 antibody GITR antibody GITR D antibody GITR-D antibody GITRD antibody Glucocorticoid induced TNFR related protein antibody glucocorticoid-induced tnf receptor ligand antibody 展开
Function :
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Purified recombinant fragment of human TNFRSF18 (AA: extra 26-162) expressed in E. Coli.
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
4H2D6
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
4℃; -20℃ for long term storage.4-(1,3-Dioxolan-2-yl)piperidine supplier
Storage buffer solution:
Purified antibody in PBS with 0.Fmoc-N-Me-Glu(OtBu)-OH Formula 05% sodium azide.PMID:33586576
Subtype:
IgG1
Purification method :
Protein G affinity purified.
ELTSA :
Molecular weight :
26kDa
Positive control :
Jurkat cells cervical cancer colon cancer