Product Name :
Pan Cadherin Recombinant Rabbit Monoclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CADH2_HUMAN antibody Cadherin 2 antibody Cadherin 2 N cadherin neuronal antibody Cadherin 2 type 1 antibody Cadherin 2 type 1 N cadherin neuronal antibody Cadherin 2 type 1 N-cadherin (neuronal) antibody Cadherin-2 antibody Cadherin2 antibody 展开
Function :
The cadherins are a large family of cell adhesion molecules involved in calcium-dependent recognition and adhesion events (1). Synaptic remodeling has been postulated as a mechanism underlying synaptic plasticity, and cadherin adhesion molecules are thought to be a regulator of such a process. Findings suggest that cadherin regulates dendritic spine morphogenesis and related synaptic functions, presumably cooperating with cadherin-independent adhesive mechanisms to maintain spine-axon contacts (2). Human retinoblastoma and normal retinal tissue the type of cadherin, its relationship with cytoplasmic catenins, and its participation in invasion has been examined. Retinoblastoma cells, in contrast with normal retina, express an cadherin-2/catenin complex that is irregularly distributed and weakly linked to the cytoskeleton. In retinoblastoma, this complex acts as an invasion promoter (3).
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
peptide
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, ICC, IHC-P, FC, IP
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20 ℃.Price of 1846598-27-3 Stable for 12 months from date of receipt
Storage buffer solution:
1*TBS (pH7.1415238-25-3 structure 4), 0.PMID:33554747 5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Tissue culture supernatant
ELTSA :
Molecular weight :
140kDa
Positive control :
C6, human cervical carcinoma tissue.